GENERAL SUMMARY/ OVERVIEW STATEMENT:
The Center for Regenerative Medicine at Massachusetts General Hospital and the department of Psychiatry at Harvard Medicial School in the Laboratory of Dr. Sundari Chetty is seeking a highly motivated individual to join our research program. The Chetty laboratory focuses on using human induced pluripotent stem cells (hiPSCs) to understand the molecular and cellular mechanisms contributing to psychiatric disorders, such as autism and schizophrenia. The candidate will work with other lab personnel as well as independently on research projects. In particular, the candidate will be responsible for maintaining and differentiating several human iPSC lines into the neuronal and glial lineages to investigate changes at the cellular, functional, and mechanistic levels using a broad range of techniques from RNA sequencing, genome editing, to functional assays in in vitro and in vivo models. Knowledge gained from these studies will be applied towards understanding the pathology and treatment of neuropsychiatric disorders (e.g. through in vitro drug screening).
The candidate will be responsible for a variety of tasks including helping manage lab supplies, onboard new lab members, and assist lab personnel with routine experiments (e.g. maintaining and expanding stem cell lines, RNA and protein isolations, flow cytometry, histological analyses, immunostaining, microscopy, quantitative PCR, etc). The candidate will also be responsible for maintaining detailed database/inventory of all lab supplies and protocols, documenting and compiling lab records and experiments, and will provide support and guidance to other laboratory personnel. Prior experience with cell culture techniques is highly desirable. The position will also involve collaborations with other labs working on related questions.
This opening is an ideal opportunity for recent college graduates and masters students interested in a career in biomedical research. Interested candidates should submit a CV, a brief statement of current and future career goals and contact information for three references.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
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