Vertex is seeking an organic chemist to join the Process Chemistry Automation Lab, a recently established group within Process Chemistry. The successful candidate will have a unique opportunity to help build our state-of-the-art automation laboratory. As a member of the team, they will work collaboratively to develop safe, efficient, and robust synthetic routes to drug candidates.
Independently design and execute high throughput experimentation (HTE) using laboratory automation to solve process chemistry problems
Develop new workflows with automation robotics, such as liquid handlers, solid handlers, high throughput analytical systems, and integrated robotic platforms
Clearly communicate HTE results to stakeholders using multi-dimensional data analysis tools (e.g. JMP, Spotfire)
Identify broad implications of data capture and data mining from HTE
Identify and advocate for innovative automation strategies to project teams
Provide training on automation equipment and HTE
Maintain laboratory automation equipment and develop new protocols
Collaborate with project teams in a cross-functional environment
Author or contribute to technical documents including regulatory submissions, patents, and scientific papers
Maintain a high level of expertise via relevant scientific and technical literature, and proactively apply new ideas to research projects.
Multitasks to effectively manage multiple activities/projects.
PhD (0+) or MS (4+) in synthetic organic chemistry
Experience independently planning, executing experiments, and interpreting analytical data (H/UPLC, NMR, MS, etc.)
Strong expertise in organic synthesis
Experience with any of the following: high throughput experimentation, laboratory automation (i.e. Chronect/QX96, Chemspeed, Unchained Labs, Hamilton, Tecan, etc.), biocatalysis, flow chemistry, cheminformatics, Python, reaction kinetic analysis